1. Thin film medical excipients are mainly composed of polyurethane materials and medical adhesives. Divided into two layers, the inner layer is a non-aqueous material that can absorb wound exudate, and the outer layer has good breathability and elasticity.

This excipient is transparent, easy to observe the wound, can tightly adhere to the surface of the wound, effectively maintain the exudate of the wound, provide a moist environment conducive to wound healing, and promote the shedding of necrotic tissue; The disadvantage is that this auxiliary material has poor water absorption performance, which can easily cause the accumulation of exudate under the skin after saturation, which may induce or worsen infection. So it is only suitable for relatively clean wounds and not for wounds with excessive exudate.

Clinical studies have shown that the application of this excipient in tracheostomy care and central venous catheterization maintenance is effective, not only in preventing infection, but also in improving patient comfort and quality of life. Worth clinical promotion and application.

2. The hydrogel medical excipient is a kind of gel like substance with three-dimensional network structure and insoluble in water, which is formed by special processing of water-soluble polymer materials or their monomers. The main components are 70% -90% pure water, carboxymethyl fiber rope, and other additional ingredients.

Clinical reports have pointed out that hydrogel medical excipients can closely fit uneven wounds, reduce the chance of bacterial growth, prevent wound infection, accelerate angiogenesis, and promote epithelial cell growth. The main function of hydrogel is self debridement, and its mechanism is to decompose necrotic substances in wet environment through collagen degrading enzymes in wound exudate.

3. Aqueous colloidal medical excipients Aqueous colloidal excipients are formed by mixing gelatin, pectin and carboxymethyl cellulose with hydrophilic gel particles.

4. foam medical excipients New foam excipients include hydrophobic outer layer and hydrophilic inner layer. This type of excipient has the characteristics of porosity, low surface tension, elasticity, strong plasticity, and lightweight. Its absorption of exudate can reach 10 times the mass of the excipient itself.

The treatment of wound exudate by foam medical excipients is controlled by the transmission and absorption mechanism of water vapor. Good plasticity, can be made into various thicknesses, and has a good protective effect on wounds. At present, polyurethane foam and polyvinyl alcohol foam are widely used. Its disadvantage is poor adhesion, requiring external fixing materials; The excipients are opaque and difficult to observe the wound surface; The auxiliary material has large pores, making it easy for new flesh tissue to grow into the wound surface, making it difficult to peel off the membrane and susceptible to bacterial contamination.

The main component of the new alginate medical excipient is algae in seawater, which is an excipient made from insoluble polysaccharide alginate similar to cellulose in algae. Alginate can combine with metal ions to form salts and is a good carrier for various metal ions. Commonly used are calcium alginate and zinc alginate excipients. Calcium alginate excipients do not cause pain from new meat damage during the replacement process and are easily accepted by patients. It can also achieve hemostasis by exchanging calcium and sodium ions, and has the function of adsorbing bacteria and preventing them from entering the wound.